Home » Klinicheskie Fenotipy Atopicheskoy Bronkhialnoy Astmy by Nenasheva Natalya
Klinicheskie Fenotipy Atopicheskoy Bronkhialnoy Astmy Nenasheva Natalya

Klinicheskie Fenotipy Atopicheskoy Bronkhialnoy Astmy

Nenasheva Natalya

Published February 22nd 2012
ISBN : 9783847390336
Paperback
328 pages
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 About the Book 

Bronkhialnaya astma ne yavlyaetsya gomogennym zabolevaniem, a skoree kompleksom razlichnykh fenotipov, trebuyushchim differentsirovannogo podkhoda k diagnostike i lecheniyu. Dolya atopicheskoy astmy sostavlyaet 78% ot obshchego chisla vzroslykhMoreBronkhialnaya astma ne yavlyaetsya gomogennym zabolevaniem, a skoree kompleksom razlichnykh fenotipov, trebuyushchim differentsirovannogo podkhoda k diagnostike i lecheniyu. Dolya atopicheskoy astmy sostavlyaet 78% ot obshchego chisla vzroslykh bolnykh. Sushchestvenno razlichayutsya klinicheskie fenotipy atopicheskoy astmy, v zavisimosti ot vozrasta nachala bolezni, a takzhe klinicheskiy fenotip atopicheskoy astmy podrostkov muzhskogo pola, v diagnostike kotorogo bolshoe znachenie imeyut bronkhoprovokatsionnye testy. Nalichie V16 Arg/Arg tipa 2-adrenoretseptora (19% u bolnykh astmoy) ne vliyaet na estestvennoe razvitie astmy, odnako opredelyaet vyrazhennost bronkhodilatatsionnogo otveta na korotkodeystvuyushchie 2-agonisty. Otmechena effektivnost i bezopasnost lokalnykh metodov allergen-spetsificheskoy immunoterapii u bolnykh atopicheskoy astmoy. Tsel terapii astmy - dostizhenie kontrolya, otsenka kotorogo dolzhna byt kompleksnoy, i vklyuchat ne tolko klinicheskie simptomy i funktsiyu legkikh, no i markery vospaleniya. Oksid azota v vydykhaemom vozdukhe yavlyaetsya odnim iz takikh markerov, osobenno znachimym dlya lits s atopicheskoy formoy astmy.